GASTROENTEROLOGY

DUSPATAL® (mebeverine)
Solvay Pharmaceuticals has been the leading source of medications for irritable bowel syndrome in Europe for more than 30 years. Thanks to a range of spasmolytic products and scientific/educational actions, Solvay Pharmaceuticals is recognized as expert in Irritable Bowel Syndrome. DUSPATAL® (mebeverine) is one of Solvay Pharmaceuticals’ major products for this chronic disease which affects at least 10% of the population. DUSPATAL® has a direct action on sodium-channels as well as on the intracellular calcium depot of gut smooth muscle cells. DUSPATAL® relieves spasms and avoids atony in the intestine. As a continuous improvement of the treatment of this disease, an innovative prolonged-release formulation of mebeverine was introduced some years ago: the microgranular capsule 200 mg.

	generic name
	brandnames
	product description
	indications
	description of indications
	worldwide availability
	date and country of first launch
	average dosages
	links

generic name
mebeverine
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brandnames
DUSPATAL® , DUSPATALIN® , COLOFAC® MR, COLOTAL®
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product description
DUSPATAL® (mebeverine) is a spasmolytic (spasm-reducing medication), with a selective action on the smooth muscle of the gastrointestinal tract, particularly of the colon.
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indications
Irritable Bowel Syndrome
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description of indications
Irritable Bowel Syndrome
DUSPATAL® (mebeverine) is used as first-line symptomatic treatment for irritable bowel syndrome (IBS). IBS is caused by a hypersensitivity of nerves in the bowels. This hypersensitivity causes the bowels to contract abnormally. Irritable bowel syndrome causes pain, bloatedness, diarrhea and constipation. Ten to twenty percent of all adults experience symptoms of IBS.
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worldwide availability
DUSPATAL® is available in 70 countries worldwide.
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date and country of first launch
1965
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average dosages
100 mg tablets : 4 tablets per day
135 mg tablets : 3 tablets per day
200 mg capsules : 2 capsules per day
suspension 10mg/ml : 6 mg/kg per day
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Links
http://www.solvay-ibs.com
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